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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CCDC18 All Species: 15.15
Human Site: T1398 Identified Species: 30.3
UniProt: Q5T9S5 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5T9S5 NP_996769.2 1454 168962 T1398 S H K N L T Y T Q P D S F K P
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_537071 1456 169626 T1397 S Q K D L T Y T Q S D S F K P
Cat Felis silvestris
Mouse Mus musculus Q640L5 1455 169723 T1399 G H K D L P L T H S E S F K P
Rat Rattus norvegicus XP_001060717 1462 170487 T1402 D H K D L P V T H S E S Y K P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508531 925 106760 I872 G T V R L T G I W G R Q Y E A
Chicken Gallus gallus XP_001232490 1295 151316 Q1242 R Q T S T E H Q K F G S Y H L
Frog Xenopus laevis Q9PW73 1335 154049 L1282 N N S S F N P L T Y A L D E N
Zebra Danio Brachydanio rerio XP_692712 779 89837 S726 T Q L E E S Q S L L Q S Q V S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P02566 1966 225108 Y1908 A N L N L Q K Y K Q L T H Q L
Sea Urchin Strong. purpuratus XP_796315 2152 245292 S2010 T D P T G S F S P P T P L K T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LW85 726 81954 K673 V L E K K V K K L E E D L G S
Baker's Yeast Sacchar. cerevisiae P25386 1790 206434 K1719 Q E I E K L A K E L D N L K A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 90.1 N.A. 84.4 83.5 N.A. 41.4 49.3 39.8 22.7 N.A. N.A. N.A. 20.2 22.9
Protein Similarity: 100 N.A. N.A. 95.4 N.A. 92.4 91.4 N.A. 51 65.2 59.5 37.2 N.A. N.A. N.A. 40 40
P-Site Identity: 100 N.A. N.A. 80 N.A. 53.3 46.6 N.A. 13.3 6.6 0 6.6 N.A. N.A. N.A. 13.3 13.3
P-Site Similarity: 100 N.A. N.A. 86.6 N.A. 66.6 66.6 N.A. 26.6 33.3 26.6 26.6 N.A. N.A. N.A. 46.6 40
Percent
Protein Identity: N.A. N.A. N.A. 22.4 20.8 N.A.
Protein Similarity: N.A. N.A. N.A. 35.7 40.7 N.A.
P-Site Identity: N.A. N.A. N.A. 0 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 0 0 0 0 9 0 0 0 9 0 0 0 17 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 9 0 25 0 0 0 0 0 0 25 9 9 0 0 % D
% Glu: 0 9 9 17 9 9 0 0 9 9 25 0 0 17 0 % E
% Phe: 0 0 0 0 9 0 9 0 0 9 0 0 25 0 0 % F
% Gly: 17 0 0 0 9 0 9 0 0 9 9 0 0 9 0 % G
% His: 0 25 0 0 0 0 9 0 17 0 0 0 9 9 0 % H
% Ile: 0 0 9 0 0 0 0 9 0 0 0 0 0 0 0 % I
% Lys: 0 0 34 9 17 0 17 17 17 0 0 0 0 50 0 % K
% Leu: 0 9 17 0 50 9 9 9 17 17 9 9 25 0 17 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 9 17 0 17 0 9 0 0 0 0 0 9 0 0 9 % N
% Pro: 0 0 9 0 0 17 9 0 9 17 0 9 0 0 34 % P
% Gln: 9 25 0 0 0 9 9 9 17 9 9 9 9 9 0 % Q
% Arg: 9 0 0 9 0 0 0 0 0 0 9 0 0 0 0 % R
% Ser: 17 0 9 17 0 17 0 17 0 25 0 50 0 0 17 % S
% Thr: 17 9 9 9 9 25 0 34 9 0 9 9 0 0 9 % T
% Val: 9 0 9 0 0 9 9 0 0 0 0 0 0 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 17 9 0 9 0 0 25 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _